New drug cocktail trial for tough colorectal cancer halted early
NCT ID NCT04294160
First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 29 times
Summary
This early-phase study tested different drug combinations in 122 adults with advanced or metastatic BRAF V600 colorectal cancer. The main goal was to understand safety, side effects, and find the best doses for future studies. The trial was terminated, but the results help guide next steps for treating this hard-to-treat cancer.
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Massachusetts General Hospital Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Novartis Investigative Site
Westmead, New South Wales, 2145, Australia
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Novartis Investigative Site
Brussels, 1000, Belgium
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Novartis Investigative Site
Leuven, 3000, Belgium
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Novartis Investigative Site
Toronto, Ontario, M5G 2M9, Canada
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Novartis Investigative Site
Dresden, 01307, Germany
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Novartis Investigative Site
Essen, 45147, Germany
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Novartis Investigative Site
Ulm, 89081, Germany
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Novartis Investigative Site
Tel Aviv, 6423906, Israel
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Novartis Investigative Site
Zoetermeer, NL-2722 EP, Netherlands
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Novartis Investigative Site
Singapore, 119228, Singapore
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Novartis Investigative Site
Barcelona, Catalonia, 08035, Spain
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Novartis Investigative Site
Valencia, Valencia, 46010, Spain
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Novartis Investigative Site
Madrid, 28009, Spain
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Novartis Investigative Site
Manchester, M20 2BX, United Kingdom
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Sarah Cannon Research Institute SC
Nashville, Tennessee, 37203, United States
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Uni Of TX MD Anderson Cancer Cntr
Houston, Texas, 77030, United States
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University of California LA Santa Monica Location
Los Angeles, California, 90095, United States
Conditions
Explore the condition pages connected to this study.