New drug duo aims to break cigarette addiction by boosting E-Cig switch

NCT ID NCT05205811

Summary

This study tested whether two prescription medications, zonisamide and bupropion, could help smokers completely switch from regular cigarettes to a JUUL e-cigarette. 180 adult smokers who wanted to switch were given the e-cigarette and then randomly assigned to receive either both medications, just bupropion, or placebo pills for 7 weeks. Researchers measured success by checking breath and urine for cigarette smoke chemicals and asking about daily use.

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Contacts and locations

Locations

  • Rose Research Center

    Charlotte, North Carolina, 28262, United States

  • Rose Research Center

    Raleigh, North Carolina, 27617, United States

Conditions

Explore the condition pages connected to this study.