New combo therapy targets rare liver cancer in early trial

NCT ID NCT06027086

First seen Dec 17, 2025 · Last updated May 08, 2026 · Updated 21 times

Summary

This study tests whether combining two drugs—DRP-104 (a glutamine blocker) and durvalumab (an immunotherapy)—is safe and can shrink tumors in people with advanced fibrolamellar carcinoma, a rare liver cancer. About 27 participants aged 12 and older whose cancer has worsened despite prior treatment will receive the drugs. The goal is to measure side effects and tumor response.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins SKCCC

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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