New hope for rare liver cancer: drug duo targets tumor fuel

NCT ID NCT06027086

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether combining a glutamine-blocking drug (DRP-104) with an immunotherapy (durvalumab) can shrink or control advanced fibrolamellar carcinoma, a rare liver cancer. About 27 people aged 12 and older whose cancer has worsened despite prior treatment will receive the drugs. The main goals are safety and tumor response.

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Conditions

The condition(s) this trial relates to.

carcinoma fibrolamellar hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins SKCCC

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact