New hope in fight against deadly asbestos cancer

NCT ID NCT04334759

Completed Disease control Sponsor: PrECOG, LLC. Source: ClinicalTrials.gov ↗

Summary

This study tested whether adding an immunotherapy drug called durvalumab to standard chemotherapy helps people with advanced pleural mesothelioma live longer. Pleural mesothelioma is an aggressive cancer often linked to asbestos exposure, with limited treatment options. The trial compared the new combination against either standard chemotherapy alone or a different immunotherapy pair.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Locations

Abramson Cancer Cener at Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, 19104, United States
Allegheny Cancer Center

Pittsburgh, Pennsylvania, 15224, United States
Auckland City Hospital

Grafton, Auckland, 1023, New Zealand
Austin Hospital

Heidelberg, Victoria, 3084, Australia
Baylor College of Medicine

Houston, Texas, 77030, United States
Blacktown Hospital

Blacktown, New South Wales, 2148, Australia
Calvary Mater Newcastle

Waratah, New South Wales, 2298, Australia
Canberra Hospital

Garran, Australian Capital Territory, 2605, Australia
Chris O'Brien Lifehouse

Camperdown, New South Wales, 2050, Australia
Cleveland Clinic Foundation

Cleveland, Ohio, 44195, United States
Coffs Harbour Health Campus

Coffs Harbour, New South Wales, 2450, Australia
Dana Farber Cancer Institute

Boston, Massachusetts, 02215, United States
Emory University

Atlanta, Georgia, 30322, United States
Epworth HealthCare - Richmond

Richmond, Victoria, 3121, Australia
Flinders Medical Centre

Bedford Park, South Australia, 5042, Australia
Gosford Hospital

Gosford, New South Wales, 2250, Australia
Goulburn Valley Health

Shepparton, Victoria, 3630, Australia
Icon Cancer Care Chermside

Chermside, Queensland, 4032, Australia
Icon Cancer Care South Brisbane

South Brisbane, Queensland, 4101, Australia
Icon Cancer Care Wesley

Auchenflower, Queensland, 4066, Australia
Jersey Shore University Medical Center

Neptune City, New Jersey, 07753, United States
Johns Hopkins Sidney Kimmel Comprehensive Cancer Center

Baltimore, Maryland, 21287, United States
Launceston General Hospital

Launceston, Tasmania, 7250, Australia
Liverpool Hospital

Liverpool, New South Wales, 2170, Australia
MD Anderson Cancer Center

Houston, Texas, 77030, United States
Massaschusetts General Hospital

Boston, Massachusetts, 02114, United States
Memorial Sloan Kettering

New York, New York, 10065, United States
Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States
Moffitt Cancer Center

Tampa, Florida, 18054, United States
Monash Health

Clayton, Victoria, 3168, Australia
Morristown Medical/Atlantic Health

Morristown, New Jersey, 07960, United States
Nepean Hospital

Kingswood, New South Wales, 2747, Australia
NorthShore University Health System/Kellogg Cancer Center

Evanston, Illinois, 60201, United States
Northern Cancer Institute (GenesisCare)

Saint Leonards, New South Wales, 2065, Australia
Orange Health Service

Orange, New South Wales, 2800, Australia
Peninsula & South Eastern Haematology and Oncology Group

Frankston, Victoria, 3199, Australia
Penn State Cancer Institute

Hershey, Pennsylvania, 17033, United States
Peter MacCallum Cancer Centre

Melbourne, Victoria, 3000, Australia
Princess Alexandra Hospital

Woolloongabba, Queensland, 4102, Australia
Royal Hobart Hospital

Hobart, Tasmania, 7000, Australia
Rutgers Cancer Institute of New Jersey

New Brunswick, New Jersey, 08903, United States
Sir Charles Gairdner Hospital (SCGH)

Nedlands, Western Australia, 6009, Australia
Sunshine Coast University Hospital

Birtinya, Queensland, 4575, Australia
Sunshine Hospital (Western Health)

Saint Albans, Victoria, 3021, Australia
The Ohio State University

Columbus, Ohio, 43210, United States
The Prince Charles Hospital

Chermside, Queensland, 4032, Australia
The Queen Elizabeth Hospital

Woodville South, South Australia, 5011, Australia
Townsville University Hospital

Douglas, Queensland, 4814, Australia
University of California San Diego

La Jolla, California, 92093, United States
University of Chicago

Chicago, Illinois, 60637, United States
University of Cincinnati

Cincinnati, Ohio, 45267, United States
University of Miami

Miami, Florida, 33136, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States
University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States
University of Virginia

Charlottesville, Virginia, 22903, United States
Westmead Hospital

Westmead, New South Wales, 2145, Australia
Wyong Hospital

Hamlyn Terrace, New South Wales, 2259, Australia

Conditions

Explore the condition pages connected to this study.

MALIGNANT PLEURAL MESOTHELIOMA MESOTHELIOMA PLEURAL MESOTHELIOMA