New combo therapy aims to stall sarcoma progression

NCT ID NCT04028063

First seen Jan 30, 2026 · Last updated Apr 29, 2026 · Updated 10 times

Summary

This study tests whether adding two immunotherapy drugs (zalifrelimab or botensilimab plus balstilimab) to standard chemotherapy (doxorubicin) can keep advanced soft tissue sarcoma from growing longer than chemo alone. About 65 adults with sarcoma that has spread or cannot be removed by surgery will receive the combination. The main goal is to see how many patients are alive without their cancer getting worse after 6 months.

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Contacts and locations

Locations

  • University of Colorado Hospital

    Aurora, Colorado, 80045, United States

Conditions

Explore the condition pages connected to this study.