New drug aims to boost daily living skills in down syndrome

NCT ID NCT07334912

First seen Jan 12, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This study tests whether a daily pill called AEF0217 can improve everyday skills like communication and self-care in adults and older teens with Down Syndrome. About 188 participants will take one of three doses of the drug or a placebo for 24 weeks. Researchers will check changes in behavior, thinking, and quality of life, while also monitoring safety.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, 33000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centro di Medicina dell'Invecchiamento, Policlinico Universitario Agostino Gemelli IRCCS

    RECRUITING

    Roma, 00168, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Genetics department, Hospices Civils de Lyon

    NOT_YET_RECRUITING

    Lyon, 69500, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Genetics department, Institut Jérôme Lejeune

    RECRUITING

    Paris, 75725, France

    Contact Phone: •••-•••-••••

    Contact Email: •••••@•••••

    Contact

  • IRCCS Istituto Delle Scienze Neurologiche, Azienda Unita Sanitaria Locale Di Bologna

    RECRUITING

    Bologna, 40139, Italy

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Integrative Pharmacology and Systems Neurosciences, Hospital del Mar Research Institute

    RECRUITING

    Barcelona, 08003, Spain

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Service Génétique Médicale, CHU de Montpellier

    RECRUITING

    Montpellier, 34295, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Service de Génétique, Chromosomique et Moléculaire, Chu de Saint Etienne

    RECRUITING

    Saint-Etienne, 42270, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Servicio de Medicina Interna, Hospital Universitario De La Princesa

    NOT_YET_RECRUITING

    Madrid, 28006, Spain

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UOR of Neurofarmacology and Translational Neurosciences, Associazione Oasi Maria S.S.Onlus

    RECRUITING

    Troina, 94018, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.