Nightly eye drops may keep Kids' vision sharp longer

NCT ID NCT07567040

Recruiting now Prevention Sponsor: Ohio State University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Aug 13, 2026 · Updated 6 times

Summary

This study tests whether a nightly drop of low-dose atropine in both eyes can delay the start of nearsightedness in children aged 6–11 who are not yet nearsighted. Over 600 kids will be randomly assigned to get either the atropine drops or placebo drops for two years. The main goal is to see if fewer children become nearsighted in the atropine group compared to the placebo group.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Atropine sulfate 0.05% eye drops
What this could lead to: If successful, this could give children a simple way to delay or prevent nearsightedness, reducing the need for glasses or contacts later.
What could go wrong: This is a Phase 3 trial, but results may not apply to all children. Atropine drops can cause light sensitivity or blurry near vision, and the effect may wear off after stopping.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

myopia prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOPIA

Contacts and locations

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Locations

Case Western Reserve Department of Ophthalmology
NOT_YET_RECRUITING

Cleveland, Ohio, 44106, United States
Illinois College of Optometry
RECRUITING

Chicago, Illinois, 60616, United States

Contact Email: •••••@•••••
Indiana University
RECRUITING

Bloomington, Indiana, 47405, United States
New England College of Optometry
RECRUITING

Boston, Massachusetts, 02115, United States

Contact Email: •••••@•••••
Pennsylvania College of Optometry at Drexel University
NOT_YET_RECRUITING

Elkins Park, Pennsylvania, 19027, United States
Rosenberg College of Optometry at the University of Incarnate Word
NOT_YET_RECRUITING

San Antonio, Texas, 78229, United States
Southern California College of Optometry at Marshall B. Ketchum University
RECRUITING

Fullerton, California, 92831, United States

Contact Email: •••••@•••••
Southern College of Optometry
NOT_YET_RECRUITING

Memphis, Tennessee, 38104, United States
Stanford University
NOT_YET_RECRUITING

Palo Alto, California, 94303, United States
State University of New York College of Optometry
RECRUITING

New York, New York, 10036, United States
The Ohio State University College of Optometry
RECRUITING

Columbus, Ohio, 43210, United States
University of Alabama School of Optometry
RECRUITING

Birmingham, Alabama, 35233, United States
University of California, Berkeley, School of Optometry
NOT_YET_RECRUITING

Berkeley, California, 94720, United States
University of Houston College of Optometry
RECRUITING

Houston, Texas, 77004, United States

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