New hope for celiac sufferers: drug targets gut damage despite strict diet

NCT ID NCT07239336

First seen Nov 20, 2025 · Last updated May 17, 2026 · Updated 23 times

Summary

This study tests a new drug called DONQ52 in 92 adults with active celiac disease who still have gut damage and symptoms like belly pain and bloating, even after trying a gluten-free diet for at least a year. The goal is to see if DONQ52 can heal the small intestine and reduce symptoms compared to a placebo. Participants will eat gluten-containing products during the trial to mimic accidental exposure.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Advanced Research Institute

    RECRUITING

    Ogden, Utah, 84405, United States

  • Advanced Research Institute Sandy

    RECRUITING

    Sandy City, Utah, 84070, United States

  • Akron Gastro Research, LLC

    RECRUITING

    Akron, Ohio, 44320, United States

  • Associates in Gastroenterology, PC

    RECRUITING

    Colorado Springs, Colorado, 80923, United States

  • Asthma and Allergy Associates, PC

    RECRUITING

    Colorado Springs, Colorado, 80907, United States

  • Care Access Research - Ogden

    RECRUITING

    Ogden, Utah, 84403, United States

  • Central Sooner Research

    RECRUITING

    Norman, Oklahoma, 73071, United States

  • Chandler Clinical Trials

    RECRUITING

    Chandler, Arizona, 85224, United States

  • Columbia Digestive Health Research

    RECRUITING

    Columbia, South Carolina, 29204, United States

  • DM Clinical Research - Cyfair Clinical Research Center

    RECRUITING

    Tomball, Texas, 77375, United States

  • Digestive Health Research of North Texas

    RECRUITING

    Wichita Falls, Texas, 76301, United States

  • Digestive Research of Central Texas, LLC

    RECRUITING

    Waco, Texas, 76301, United States

  • East View Medical Research

    RECRUITING

    Mobile, Alabama, 36608, United States

  • GI Alliance Rhode Island

    RECRUITING

    Providence, Rhode Island, 02905, United States

  • GMC Clinical Research, LLC

    RECRUITING

    Folsom, California, 95630, United States

  • Global Life Research Network

    RECRUITING

    Miami, Florida, 33155, United States

  • Great Lakes Gastroenterology Research, LLC

    RECRUITING

    Mentor, Ohio, 44060, United States

  • Guardian Angel Research Center

    RECRUITING

    Tampa, Florida, 33614, United States

  • Mater

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Mountain View Clinical Research, Inc.

    RECRUITING

    Denver, Colorado, 80209, United States

  • Novum Clinical Research

    RECRUITING

    Clermont, Florida, 34711, United States

  • Oasis Clinical Research

    RECRUITING

    Las Vegas, Nevada, 89121, United States

  • Ocala GI Research

    RECRUITING

    Ocala, Florida, 34471, United States

  • Om Research LLC

    RECRUITING

    Lancaster, California, 93534, United States

  • One of a Kind Clinical Research Center LLC

    RECRUITING

    Scottsdale, Arizona, 85258, United States

  • Pinnacle Research Group, LLC

    RECRUITING

    Anniston, Alabama, 36207, United States

  • Portland Gastroenterology Center

    RECRUITING

    Portland, Maine, 04101, United States

  • Research Solutions of Arizona, PC

    RECRUITING

    Litchfield, Arizona, 85340, United States

  • Scottsdale Clinical Trials

    RECRUITING

    Scottsdale, Arizona, 85260, United States

  • Stamford Therapeutics Consortium

    RECRUITING

    Stamford, Connecticut, 06905, United States

  • Susquehanna Research Group, LLC

    RECRUITING

    Harrisburg, Pennsylvania, 17110, United States

  • University of The Sunshine Coast Clinical Trials Centre (Sippy Downs)

    RECRUITING

    Sippy Downs, Queensland, 4556, Australia

  • University of the Sunshine Coast Clinical Trials Centre

    RECRUITING

    Morayfield, Queensland, 4506, Australia

  • University of the Sunshine Coast Clinical Trials Centre (SouthBank)

    RECRUITING

    South Brisbane, Queensland, 4101, Australia

  • Velocity Clinical Research, Gardena

    RECRUITING

    Gardena, California, 90247, United States

  • Velocity Clinical Research, Salt Lake City

    RECRUITING

    West Jordan, Utah, 84088, United States

  • Vitality Clinical Research

    RECRUITING

    Katy, Texas, 77494, United States

  • Wellness Clinical Research

    RECRUITING

    Miami Lakes, Florida, 33016, United States

Conditions

Explore the condition pages connected to this study.