New pill targets Hard-to-Treat cancers with specific gene mutation

NCT ID NCT05752552

First seen Apr 07, 2026 · Last updated May 02, 2026 · Updated 3 times

Summary

This early-phase study tests a new oral drug, DO-2, in adults with advanced solid tumors (like lung cancer) that have a specific MET gene change and no standard treatment options left. The main goal is to check the drug's safety and find the right dose. About 55 participants will take the pill, and researchers will monitor side effects and any tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Antoine Lacassagne

    NOT_YET_RECRUITING

    Nice, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier Universitaire De Rennes

    RECRUITING

    Rennes, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Léon Bérard

    RECRUITING

    Lyon, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

    RECRUITING

    Rotterdam, Netherlands

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpitaux Universitaires de Marseille Timone

    NOT_YET_RECRUITING

    Marseille, 13385, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Bergonie

    RECRUITING

    Bordeaux, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Cœur Poumon - CHU Lille

    RECRUITING

    Lille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Gustave Roussy

    NOT_YET_RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Institut Roi Albert II - UC Louvain

    RECRUITING

    Brussels, Belgium

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Radboud UMC

    RECRUITING

    Nijmegen, Netherlands

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZ Leuven

    RECRUITING

    Leuven, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UZA

    RECRUITING

    Edegem, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Universitair Ziekenhuis Gent

    RECRUITING

    Ghent, 9000, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.