New hope for diabetic eye patients: study tests steroid implant after standard treatment fails

NCT ID NCT05978622

Summary

This study follows patients with diabetic macular edema (DME), a vision-threatening eye swelling, who didn't respond well to standard anti-VEGF injections. Doctors will observe how these patients do when switched to a slow-release steroid implant (DEX-I) in their regular clinical care. The study will track about 236 patients across 10 countries for 18 months to see how this treatment change works in real-world practice.

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Contacts and locations

Locations

  • ASU FC - P.O. Universitario Santa Maria della Misericordia /ID# 256293

    Udine, 33100, Italy

  • Augenzentrum Am Johannisplatz /ID# 255754

    Leipzig, 04103, Germany

  • Augenzentrum Frankfurt /ID# 255576

    Frankfurt am Main, 60549, Germany

  • Augenzentrum Frohe Zukunft /ID# 256290

    Halle, 06118, Germany

  • Augenzentrum Prinz 25 /ID# 261090

    Augsburg, 86150, Germany

  • Bradford Teaching hospitals/ Bradford macular centre /ID# 260909

    Bradford, BD5 0JD, United Kingdom

  • CHR de la Citadelle /ID# 257254

    Liège, 4000, Belgium

  • CHU Saint Pierre /ID# 257650

    Brussels, Brussels Capital, 1000, Belgium

  • Centro Hospitalar do Baixo Vouga /ID# 264421

    Porto, 3814-501, Portugal

  • China Medical University Hospital /ID# 262427

    Taichung, 40447, Taiwan

  • Derriford Hospital and the Royal Eye Infirmary /ID# 260908

    Plymouth, Devon, PL6 8DH, United Kingdom

  • Dres. Schubert/Wissmann /ID# 261598

    Ettlingen, 76275, Germany

  • East Cheshire NHS Trust /ID# 270263

    Macclesfield, SK10 3BL, United Kingdom

  • Eye Clinic of Athens /ID# 258749

    Athens, 10672, Greece

  • Far Eastern Memorial Hospital /ID# 262428

    New Taipei City, 22060, Taiwan

  • Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Universita Cattolica /ID# 258134

    Rome, Roma, 00168, Italy

  • General Hospital of Lamia /ID# 265442

    Lamia, 35100, Greece

  • Gloucestershire Hospitals NHS Foundation Trust /ID# 256886

    Cheltenham, Gloucestershire, GL53 7AN, United Kingdom

  • Great Western Hospital /ID# 258467

    Swindon, SN3 6BB, United Kingdom

  • Hospital de Santa Maria Maior, EPE /ID# 261063

    Barcelos, Braga District, 4750-275, Portugal

  • IRCCS Fondazione G.B. Bietti per lo studio e la ricerca in Oftalmologia- ONLUS /ID# 258039

    Rome, Roma, 00184, Italy

  • Kaohsiung Veterans General Hospital /ID# 262429

    Kaohsiung City, 813, Taiwan

  • Kaplan Medical Center /ID# 265471

    Rehovot, Central District, 7660101, Israel

  • Linkou Chang Gung Memorial Hospital /ID# 256091

    Taoyuan, 333, Taiwan

  • Liverpool University Hospitals NHS Foundation Trust /ID# 260230

    Liverpool, Merseyside, L9 7AL, United Kingdom

  • MVZ Augenzentrum am Berliner Ring /ID# 267412

    Würzburg, Bavaria, 97080, Germany

  • MVZ der Klinik Dardenne GmbH Makulazentrum /ID# 269798

    Bonn, North Rhine-Westphalia, 53177, Germany

  • Moorfields Eye Hospital /ID# 258465

    London, Greater London, EC1V 2PD, United Kingdom

  • National Taiwan University Hospital /ID# 262426

    Taipei City, Taipei, 100, Taiwan

  • Opthalmica SA /ID# 258748

    Thessaloniki, 54643, Greece

  • Papageorgiou General Hospital /ID# 265500

    Thessaloniki, 56429, Greece

  • Qingdao Eye Hospital Of Shandong First Medical University /ID# 262756

    Qingdao, Shandong, 266071, China

  • Rabin Medical Center /ID# 265476

    Petah Tikva, Central District, 4941492, Israel

  • Reg Gen Univ Hosp Larissa /ID# 255235

    Larissa, 41110, Greece

  • Royal Victoria Hospital /Id# 260232

    Belfast, BT12 6BA, United Kingdom

  • Shenzhen Eye Hospital /ID# 262954

    Shenzhen, Guangdong, 518034, China

  • Sunderland Eye Infirmary /ID# 258466

    Sunderland, SR2 9HP, United Kingdom

  • Tel Aviv Sourasky Medical Center /ID# 265469

    Tel Aviv, Tel Aviv, 6423906, Israel

  • Tongji Hospital /ID# 270275

    Wuhan, Hubei, 430030, China

  • Unidade Local de Saude da Regiao de Leiria, EPE /ID# 262009

    Leiria, 2410-197, Portugal

  • Unidade Local de Saude de Santo Antonio, E.P.E. /ID# 262010

    Porto, 4099-003, Portugal

  • Unidade Local de Saude do Estuario do Tejo, EPE /ID# 267945

    Vila Franca de Xira, 2600-009, Portugal

  • Universita Politecnica delle Marche - AOU Ospedali Riuniti di Ancona /ID# 258072

    Ancona, 60126, Italy

  • Universitaetsklinikum Leipzig /ID# 255660

    Leipzig, Saxony, 04103, Germany

  • Universitair Ziekenhuis Brussel /ID# 255324

    Jette, Brussels Capital, 1090, Belgium

  • University General Hospital Attikon /ID# 257957

    Athens, Attica, 12462, Greece

  • University General Hospital of Alexandroupoli /ID# 275850

    Alexandroupoli, Evros, 68100, Greece

  • University General Hospital of Heraklion PA.G.N.I /ID# 258313

    Heraklion, Crete, 71500, Greece

  • Università di Torino /ID# 258442

    Torino, 10124, Italy

  • Uza /Id# 255831

    Edegem, Antwerpen, 2650, Belgium

  • Vitaz /Id# 265553

    Sint-Niklaas, Oost-Vlaanderen, 9100, Belgium

  • West China Hospital, Sichuan University /ID# 262745

    Chengdu, Sichuan, 610041, China

  • Xi'an Fourth Hospital /ID# 262972

    Xi'an, Shaanxi, 710004, China

  • Ziekenhuis Oost-Limburg, Campus St.-Jan /ID# 255934

    Genk, Limburg, 3600, Belgium

Conditions

Explore the condition pages connected to this study.