Simple blood test could Fine-Tune breast cancer drug dosing

NCT ID NCT06572800

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 30 times

Summary

This study tested whether a blood test called DiviTum-TKa can help doctors check if patients with advanced breast cancer are taking their CDK4/6 inhibitor medication correctly and if other drugs are interfering. The test measures a marker of cell growth. Researchers hoped to see if using the test could improve how well the medication works. The study involved 34 patients with ER/PR positive, HER2-negative breast cancer that had spread.

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Contacts and locations

Locations

  • Smilow Cancer Center/Yale-New Haven Hospital

    New Haven, Connecticut, 06510, United States

  • Smilow Cancer Hospital Care Center - Guilford

    Guilford, Connecticut, 06437, United States

  • Smilow Cancer Hospital Care Center - Waterford

    Waterford, Connecticut, 06385, United States

  • Smilow Cancer Hospital Care Center - Westerly

    Westerly, Rhode Island, 02891, United States

  • Smilow Cancer Hospital Care Center at Glastonbury

    Glastonbury, Connecticut, 06033, United States

  • Smilow Cancer Hospital Care Center at Greenwich

    Greenwich, Connecticut, 06830, United States

  • Smilow Cancer Hospital Care Center at Long Ridge

    Stamford, Connecticut, 06902, United States

  • Smilow Cancer Hospital Care Center at Saint Francis

    Hartford, Connecticut, 06105, United States

  • Smilow Cancer Hospital Care Center-Fairfield

    Fairfield, Connecticut, 06824, United States

  • Smilow Cancer Hospital Care Center-Trumbull

    Trumbull, Connecticut, 06611, United States

  • Smilow Cancer Hospital-Derby Care Center

    Derby, Connecticut, 06418, United States

  • Smilow Cancer Hospital-Hamden Care Center

    Hamden, Connecticut, 06518, United States

  • Smilow Cancer Hospital-Orange Care Center

    Orange, Connecticut, 06477, United States

  • Smilow Cancer Hospital-Torrington Care Center

    Torrington, Connecticut, 06790, United States

  • Smilow Cancer Hospital-Waterbury Care Center

    Waterbury, Connecticut, 06708, United States

  • Yale University

    New Haven, Connecticut, 06520, United States

  • Yale-New Haven Hospital North Haven Medical Center

    North Haven, Connecticut, 06473, United States

  • Yale-New Haven Hospital Saint Raphael Campus

    New Haven, Connecticut, 06511, United States

Conditions

Explore the condition pages connected to this study.