New drug duo aims to stop bladder cancer from coming back

NCT ID NCT07646145

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This phase II trial is testing a combination of two drugs—disitamab vedotin given through a vein and mitomycin C placed directly into the bladder—in 30 people with a specific type of non-muscle-invasive bladder cancer that has a protein called HER2. The goal is to see if this treatment can reduce the risk of the cancer returning and help patients avoid more aggressive surgery to remove the bladder.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Disitamab vedotin (an antibody-drug conjugate) and mitomycin C (a chemotherapy drug given directly into the bladder)

What this could lead to

If this works, it could offer a new treatment option that lowers the chance of bladder cancer coming back and helps patients avoid needing their bladder removed.

What could go wrong

This is a small, early-phase trial with only 30 participants, so results may not apply to everyone. The combination of drugs may cause side effects, and it is not yet known if it works better than standard care.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

non-invasive bladder urothelial carcinoma Non-Muscle Invasive Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanxi Provincial Cancer Hospital

    RECRUITING

    Taiyuan, Shanxi, 030000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••