Sound waves open brain barrier to attack deadly childhood tumor
NCT ID NCT05630209
First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 20 times
Summary
This study tests whether using focused ultrasound to temporarily open the blood-brain barrier can safely deliver the chemotherapy drug doxorubicin to treat a rare and aggressive brain tumor called DIPG in children and young adults aged 5 to 21. The approach aims to improve drug access to the tumor while reducing side effects. The trial monitors for adverse events and measures how well the barrier is disrupted using MRI scans.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Children's National Medical Center
Washington D.C., District of Columbia, 20010, United States
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Cook Children's Health Care System
Fort Worth, Texas, 76104, United States
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Nicklaus Children's Hospital
Miami, Florida, 33155, United States
Conditions
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