New hope for kids with devastating brain cancer: First-in-Human vaccine trial begins

NCT ID NCT04943848

Summary

This is a first-in-human safety study testing a new, 'off-the-shelf' cancer vaccine combined with two immunotherapy drugs for children with DIPG and DMG, aggressive brain tumors with very few treatment options. The trial aims to see if this combination is safe and tolerable for children aged 1 to 18 who have recently finished radiation therapy. Researchers hope this approach will train the immune system to attack the tumor and improve outcomes for these high-risk patients.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann and Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Children's Health Orange County (CHOC)

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dana-Farber Boston Children's Cancer and Blood Disorders Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.