Chest wrinkle treatment shows promise in new study

NCT ID NCT05163353

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether diluted Radiesse injections can safely reduce wrinkles on the décolleté (upper chest). 152 women aged 30 to 65 received the treatment. At 24 weeks, more than half showed at least a one-point improvement on a wrinkle severity scale.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
diluted Radiesse (calcium hydroxylapatite)
What this could lead to
If successful, this could offer a safe, effective option for reducing wrinkles on the upper chest area.
What could go wrong
This is a cosmetic treatment, not a cure for any disease. Results may vary, and risks include injection-related side effects like swelling or bruising.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Clinical Testing of Beverly Hills, Merz Investigational Site #0010395

    Beverly Hills, California, 90210, United States

  • Cosmetic Laser Dermatology, Merz Investigational Site #0010321

    San Diego, California, 92121, United States

  • Face Beautiful Inc, Merz Investigational Site #0010358

    Vista, California, 92083, United States

  • Facial Plastic Surgery, Merz Investigational Site #0010463

    Redondo Beach, California, 90277, United States

  • Nashville Center for Laser and Facial Surgery, Merz Investigational Site #0010353

    Nashville, Tennessee, 37203, United States

  • Private Practice, Merz Investigational Site #0010299

    Santa Monica, California, 90404, United States

  • Research Institute of the Southeast, LLC, Merz Investigational Site #0010420

    West Palm Beach, Florida, 33401, United States

  • Skin Associates of South Florida, Merz Investigational Site #0010101

    Coral Gables, Florida, 33146, United States

  • The Graivier Center, Merz Investigational Site #0010464

    Alpharetta, Georgia, 30005, United States

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