Could a malaria pill tame discoid lupus?
NCT ID NCT07557927
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether dihydroartemisinin, a drug used for malaria, can help treat discoid lupus erythematosus (DLE), a chronic skin condition causing red, scaly patches. Researchers will compare two doses of the drug to a standard lupus treatment (hydroxychloroquine) in 100 adults over 24 weeks. The goal is to see if it reduces skin severity and is safe.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dihydroartemisinin tablets
- What this could lead to
- If it works, this could offer a new treatment option for discoid lupus, a chronic skin condition, potentially with fewer side effects than current therapies.
- What could go wrong
- This is an early Phase 2 trial with only 100 people, so results may not apply to everyone. It's also not a cure—patients would still need ongoing management.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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China-Japan Friendship Hospital
Beijing, Beijing Municipality, China
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Hangzhou Third People's Hospital
Hangzhou, Zhejiang, China
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Nanfang Hospital, Southern Medical University
Guangzhou, Guangdong, China
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Peking University People's Hospital
Beijing, Beijing Municipality, China
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Sun Yat-sen Memorial Hospital, Sun Yat-sen University
Guangzhou, Guangdong, China
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The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China
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The First Affiliated Hospital of China Medical University
Shenyang, Liaoning, China
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The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, China
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The Second Affiliated Hospital of Kunming Medical University
Kunming, Yunnan, China
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The Second Xiangya Hospital of Central South University
Changsha, Hunan, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.