App-Based treatment shows promise for alcohol addiction
NCT ID NCT05748639
First seen Nov 20, 2025 · Last updated Jun 20, 2026 · Updated 27 times
Summary
This completed trial tested a digital health app (QG-A) that combines cognitive-behavioral therapy with the medication naltrexone to help adults with moderate to severe alcohol use disorder reduce their drinking. 242 participants were randomly assigned to either the app-based program or standard medical care. The study aimed to see if the digital approach was more effective at cutting alcohol use and improving mental health.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Quit Genius
New York, New York, 10001, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
naltrexone
What this could lead to
If successful, this could provide an effective, scalable digital treatment option for alcohol use disorder that combines medication and therapy.
What could go wrong
The trial is completed but results are not yet widely reported. The digital approach may not work for everyone, and participants must be willing to take naltrexone, which can have side effects.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.