App-Based treatment shows promise for alcohol addiction

NCT ID NCT05748639

Completed Disease control Sponsor: Quit Genius Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed trial tested a digital health app (QG-A) that combines cognitive-behavioral therapy with the medication naltrexone to help adults with moderate to severe alcohol use disorder reduce their drinking. 242 participants were randomly assigned to either the app-based program or standard medical care. The study aimed to see if the digital approach was more effective at cutting alcohol use and improving mental health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: naltrexone
What this could lead to: If successful, this could provide an effective, scalable digital treatment option for alcohol use disorder that combines medication and therapy.
What could go wrong: The trial is completed but results are not yet widely reported. The digital approach may not work for everyone, and participants must be willing to take naltrexone, which can have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ALCOHOL USE DISORDER

Contacts and locations

Locations

Quit Genius

New York, New York, 10001, United States

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