New cocktail of charcoal and laxative could speed up poison recovery
NCT ID NCT07201311
First seen Jun 24, 2026 · Last updated Jul 07, 2026 · Updated 4 times
Summary
This study tests whether giving a combination of activated charcoal and polyethylene glycol (a laxative) can reduce the amount of toxic drugs absorbed in the gut for people with severe poisoning in intensive care. Two hundred adults on ventilators will be randomly assigned to get either the combined treatment or standard care with charcoal alone. The main goal is to see if drug levels in the blood drop more after 24 hours with the combined approach.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- activated charcoal and polyethylene glycol
- What this could lead to
- If it works, this could improve how quickly toxic drugs are removed from the body in severe poisoning cases, potentially reducing ICU stay and complications.
- What could go wrong
- This is a small, early-phase study (Phase 2) with only 200 patients. The treatment may not significantly lower drug levels, and side effects like bowel obstruction or electrolyte imbalances are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sebastian Voicu
RECRUITINGParis, 75010, France