New heart ablation tool shows promise for persistent AF patients

NCT ID NCT03643224

First seen Nov 01, 2025 · Last updated May 24, 2026 · Updated 23 times

Summary

This study tested a new device called the DiamondTemp Ablation System to treat people with persistent atrial fibrillation (a type of irregular heartbeat) that medication couldn't control. Researchers wanted to see if the device could safely restore a normal heart rhythm for at least 12 months. The study involved 376 adults with persistent AF, and the main goal was to check for serious side effects and how well the treatment worked.

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Contacts and locations

Locations

  • Advent Health, Florida Hospital Orlando

    Orlando, Florida, 32751, United States

  • CHRU Nancy

    Nancy, 54511, France

  • Centro Cardiologico Monzino

    Milan, Milano, 20138, Italy

  • Clinique Pasteur

    Toulouse, 31076, France

  • Clinique Saint Pierre

    Perpignan, 66000, France

  • Clinique du Tonkin

    Villeurbanne, Lyon, 69100, France

  • Grandview Medical Center

    Birmingham, Alabama, 35242, United States

  • Houston Methodist Hospital

    Houston, Texas, 77030, United States

  • Icahn School of Medicine at Mount Sinai

    New York, New York, 10029, United States

  • Institut Klinicke a Experimentalni Mediciny (IKEM)

    Prague, Czechia, 14021, Czechia

  • Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ)

    Québec, Quebec, G1V4G5, Canada

  • Iowa Heart Center

    West Des Moines, Iowa, 50266, United States

  • Jackson Heart Clinic

    Jackson, Mississippi, 39216, United States

  • Kansas City Heart Rhythm Institute

    Overland Park, Kansas, 66211, United States

  • Keck School Of Medicine

    Los Angeles, California, 90033, United States

  • Leipzig Heart Institute GmbH

    Leipzig, 04289, Germany

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Medical University Of South Carolina

    Charleston, South Carolina, 29425, United States

  • Montefiore Medical Center

    New York, New York, 10467, United States

  • Montreal Heart Institute

    Montreal, Quebec, HITC8, Canada

  • Na Homolce

    Prague, Prague, 15000, Czechia

  • North Mississippi Medical Center

    Tupelo, Mississippi, 38801, United States

  • Ospedale dell'Angelo

    Venezia, 30174, Italy

  • Southlake Regional Health Center

    Newmarket, Ontario, L3Y2P6, Canada

  • St Ann's University Hospital

    Brno, 65691, Czechia

  • Texas Cardiac Arrhythmia Research Foundation

    Austin, Texas, 78705, United States

  • Trident Medical Center

    Charleston, South Carolina, 29406, United States

  • University Of Alabama

    Birmingham, Alabama, 35294, United States

Conditions

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