Blood test could predict radiation dry mouth before it starts

NCT ID NCT07170358

First seen Jun 26, 2026 ยท Last updated Jun 26, 2026

Summary

This study is looking for early biological markers in the blood that could predict dry mouth caused by radiation therapy in head and neck cancer patients. Researchers will collect blood samples from 126 patients before and after treatment and use advanced techniques to find these markers. The goal is to identify dry mouth early so doctors can intervene sooner and improve patients' quality of life.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test to predict dry mouth before symptoms start, allowing early treatment and better quality of life.
What could go wrong
This is an early-stage observational study, not a treatment trial. The biomarkers found may not be accurate enough for routine use, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

Head and Neck Neoplasms Xerostomia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Affiliated Jinling Hospital, Medical School of Nanjing University

    RECRUITING

    Nanjing, Jiangsu, China

  • Jiangsu Cancer Hospital

    RECRUITING

    Nanjing, Jiangsu, China

  • The First Affiliated Hospital of Nanjing Medical University

    NOT_YET_RECRUITING

    Nanjing, Jiangsu, 210018, China

  • The Second Affiliated Hospital of Zhejiang University School of Medicine

    RECRUITING

    Hangzhou, Zhejiang, China