New diabetes combo aims for better long-term blood sugar control

NCT ID NCT06246799

First seen Mar 16, 2026 · Last updated May 24, 2026 · Updated 15 times

Summary

This study tests whether a combination of pioglitazone and tirzepatide works better than metformin plus sitagliptin for people recently diagnosed with type 2 diabetes. About 256 adults aged 18-75 who are either not on diabetes drugs or only on metformin will take part. The goal is to see which combo keeps blood sugar (HbA1c) below 6.5% for longer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UT Health Science Center

    RECRUITING

    San Antonio, Texas, 78229, United States

  • University Health System Texas Diabetic Institute

    RECRUITING

    San Antonio, Texas, 78207, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.