New nasal spray could quickly calm acute anxiety
NCT ID NCT07550881
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a nasal spray containing dexmedetomidine can quickly reduce symptoms of acute anxiety in adults. 150 participants will receive either the drug or a placebo, and researchers will track anxiety levels over two hours. The goal is to see if the spray is safe and effective for calming sudden, intense anxiety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexmedetomidine hydrochloride nasal spray
- What this could lead to
- If it works, this could provide a fast-acting, non-invasive treatment option for sudden, severe anxiety episodes.
- What could go wrong
- This is an early Phase 2 trial with only 150 people, so results may not apply broadly. The drug can cause drowsiness and lower blood pressure or heart rate.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Tongji Hospital Affiliated with Tongji University
RECRUITINGShanghai, Shanghai Municipality, 200032, China