New drug may reduce pain and opioid use in tiniest patients

NCT ID NCT07493785

First seen Apr 11, 2026 · Last updated May 02, 2026 · Updated 5 times

Summary

This study tests whether dexmedetomidine, a sedative that does not slow breathing, can reduce the need for opioids in premature babies who need a breathing tube. About 246 infants born before 32 weeks will receive either the drug or a placebo. The goal is to see if it helps them come off the ventilator sooner and supports better brain development.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AP-HP Hôpital Necker Enfants Malades

    Paris, 75015, France

    Contact Email: •••••@•••••

  • CHRU Lille

    Lille, 59000, France

    Contact Email: •••••@•••••

  • CHU Brest - Hôpital Morvan

    Brest, 29609, France

    Contact Email: •••••@•••••

  • CHU Félix Guyon (Saint Denis)

    Saint-Denis, 97400, France

    Contact Email: •••••@•••••

  • CHU Grenoble Alpes

    Grenoble, 38700, France

    Contact Email: •••••@•••••

  • CHU Limoges

    Limoges, 87042, France

    Contact Email: •••••@•••••

  • CHU de La Réunion - Site Sud Saint-Pierre

    Saint-Pierre, 97400, France

    Contact Email: •••••@•••••

  • CHU de Nantes

    Nantes, 44000, France

    Contact Email: •••••@•••••

  • CHU de Nice

    Nice, 6200, France

    Contact Email: •••••@•••••

  • Centre Hospitalier Intercommunal de Créteil

    Créteil, 94000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Centre Hospitalier de Saint -Denis

    Saint-Denis, 93200, France

    Contact Email: •••••@•••••

  • Hôpital NOVO - Site de Pontoise

    Pontoise, 95300, France

    Contact Email: •••••@•••••

Conditions

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