Could a tiny dose of dexmedetomidine double Pain-Free time after surgery?

NCT ID NCT07651488

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This trial tests whether adding a small dose of dexmedetomidine to a standard spinal anesthetic (bupivacaine) can extend pain relief for adults undergoing perianal surgery. One hundred participants aged 40–80 will receive either the standard anesthetic alone or with dexmedetomidine. The main goal is to see how long pain relief lasts and whether it reduces the need for additional pain medication.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
dexmedetomidine
What this could lead to
If it works, this could provide longer-lasting pain relief after perianal surgery, reducing the need for additional painkillers.
What could go wrong
This is a very early-phase trial with only 100 participants, so results may not apply broadly. Adding dexmedetomidine may also increase side effects like drowsiness or low blood pressure.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Liaquat National Hospital

    Karachi, Pakistan

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