Can a sedative calm the Body's surgical storm?

NCT ID NCT07743853

Not yet recruiting Symptom relief Sponsor: Poznan University of Medical Sciences Source: ClinicalTrials.gov ↗

First seen Aug 04, 2026 · Last updated Aug 05, 2026 · Updated 1 time

Summary

This trial tests whether giving the sedative dexmedetomidine during hip replacement surgery can dampen the body's stress and inflammatory response to the operation. Researchers will compare two doses of the drug against a placebo in 90 adults aged 50-90 undergoing total hip arthroplasty. The goal is to see if it reduces inflammation, pain, and opioid use, and improves overall recovery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Dexmedetomidine, a sedative drug given intravenously during surgery
What this could lead to: If effective, this could point to a simple way to reduce post-surgical inflammation, pain, and opioid use, speeding up recovery after hip replacement.
What could go wrong: This is a small, early-stage trial, and the results may not apply to all patients. Dexmedetomidine can cause side effects like low blood pressure or slow heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

osteoarthritis, hip

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP OSTEOARTHRITIS

Contacts and locations

Locations

Poznan University of Medical Sciences

Poznan, 62-701, Poland

More trials for these conditions

Other studies related to the condition(s) this trial covers.