Psoriasis drug trial for sensitive areas halted early

NCT ID NCT06042920

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested the drug deucravacitinib (SOTYKTU) in 130 people with psoriasis on the palms, soles, and genitals. The goal was to see if it improves skin clearance and reduces symptoms. The trial was terminated early, so final results are limited.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Deucravacitinib (SOTYKTU)
What this could lead to
If successful, this could provide a new treatment option for hard-to-treat psoriasis on the palms, soles, and genitals.
What could go wrong
The study was terminated early, so results are limited. As a phase 4 trial, safety and efficacy data may not be fully conclusive.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Local Institution - 0001

    Winston-Salem, North Carolina, 27157, United States

  • Local Institution - 0002

    New York, New York, 10003, United States

  • Local Institution - 0004

    Santa Monica, California, 90404, United States

  • Local Institution - 0005

    East Windsor, New Jersey, 08520-2505, United States

  • Local Institution - 0007

    Norfolk, Virginia, 23502-3933, United States

  • Local Institution - 0008

    New York, New York, 10075, United States

  • Local Institution - 0009

    Los Angeles, California, 90045-3606, United States

  • Local Institution - 0010

    Houston, Texas, 77004, United States

  • Local Institution - 0012

    Detroit, Michigan, 48202-3141, United States

  • Local Institution - 0015

    Fountain Valley, California, 92708, United States

  • Local Institution - 0029

    Rockville, Maryland, 20850-6243, United States

  • Local Institution - 0033

    Mill Creek, Washington, 98012-1797, United States

  • Local Institution - 0034

    Ciudad Autonoma Buenos Aires, C, C1425DKG, Argentina

  • Local Institution - 0037

    Ciudad Autónoma Buenos Aires, B, C1428DZF, Argentina

  • Local Institution - 0042

    Rosario, S, 2000, Argentina

  • Local Institution - 0043

    Ciudad Autónoma Buenos Aires, B, 1425, Argentina

  • Local Institution - 0050

    Phoenix, Arizona, 85006-2722, United States

  • Local Institution - 0052

    Indianapolis, Indiana, 46250, United States

  • Local Institution - 0053

    Plainfield, Indiana, 46168-2792, United States

  • Local Institution - 0054

    Montreal, Quebec, H2X 2V1, Canada

  • Local Institution - 0055

    Mayfield Heights, Ohio, 44124-4005, United States

  • Local Institution - 0056

    Pittsburgh, Pennsylvania, 15213-3403, United States

  • Local Institution - 0057

    Skokie, Illinois, 60077-1049, United States

  • Local Institution - 0058

    Newmarket, Ontario, L3Y 5G8, Canada

  • Local Institution - 0059

    Québec, Quebec, G1W 4R4, Canada

  • Local Institution - 0060

    Toronto, Ontario, M3B 0A7, Canada

  • Local Institution - 0061

    Saint-Jérôme, Quebec, J7Z 7E2, Canada

  • Local Institution - 0062

    New York, New York, 10128, United States

  • Local Institution - 0064

    Saskatoon, Saskatchewan, S7K 2C1, Canada

  • Local Institution - 0065

    Montreal, Quebec, H1Y 3L1, Canada

  • Local Institution - 0066

    Boardman, Ohio, 44512, United States

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