Experimental CAR t therapy for myeloma shows early promise but trial halted

NCT ID NCT06304636

First seen Dec 08, 2025 · Last updated May 10, 2026 · Updated 18 times

Summary

This early-phase study tested a new treatment called Descartes-15 for people with multiple myeloma that had come back or stopped responding to other therapies. The treatment uses a patient's own immune cells, engineered with RNA to target cancer cells. Only 4 people were enrolled before the study was stopped, so results are very limited.

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Contacts and locations

Locations

  • Center for Cancer and Blood Disorders (AON)

    Bethesda, Maryland, 20817, United States

Conditions

Explore the condition pages connected to this study.