New depression pill shows promise in Late-Stage trial

NCT ID NCT06786624

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 22 times

Summary

This study tests whether adding NBI-1065845 to standard antidepressants can better relieve depression symptoms. About 200 adults with major depression who haven't fully responded to current meds will receive either the study drug or a placebo for 8 weeks. The main goal is to see if depression scores improve more with the new drug.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Neurocrine Clinical Site

    RECRUITING

    Little Rock, Arkansas, 72204, United States

  • Neurocrine Clinical Site

    COMPLETED

    Garden Grove, California, 92844, United States

  • Neurocrine Clinical Site

    RECRUITING

    Orange, California, 92866, United States

  • Neurocrine Clinical Site

    RECRUITING

    Pico Rivera, California, 90660, United States

  • Neurocrine Clinical Site

    RECRUITING

    San Diego, California, 92103, United States

  • Neurocrine Clinical Site

    RECRUITING

    Upland, California, 91786, United States

  • Neurocrine Clinical Site

    RECRUITING

    Hollywood, Florida, 33024, United States

  • Neurocrine Clinical Site

    RECRUITING

    Maitland, Florida, 32751, United States

  • Neurocrine Clinical Site

    RECRUITING

    Boston, Massachusetts, 02116, United States

  • Neurocrine Clinical Site

    SUSPENDED

    Watertown, Massachusetts, 02472, United States

  • Neurocrine Clinical Site

    RECRUITING

    Mount Kisco, New York, 10549, United States

  • Neurocrine Clinical Site

    RECRUITING

    Avon Lake, Ohio, 44012, United States

  • Neurocrine Clinical Site

    COMPLETED

    Westlake, Ohio, 44145, United States

  • Neurocrine Clinical Site

    RECRUITING

    Dallas, Texas, 75251, United States

  • Neurocrine Clinical Site

    RECRUITING

    Houston, Texas, 77030, United States

  • Neurocrine Clinical Site

    WITHDRAWN

    Richmond, Texas, 77407, United States

  • Neurocrine Clinical Site

    SUSPENDED

    The Woodlands, Texas, 77381, United States

  • Neurocrine Clinical Site

    RECRUITING

    Everett, Washington, 98201, United States

Conditions

Explore the condition pages connected to this study.