New depression pill DT120 shows promise in phase 3 trial

NCT ID NCT07592689

First seen May 19, 2026 · Last updated May 21, 2026 · Updated 1 time

Summary

This study tests an experimental oral medication called DT120 for adults with major depressive disorder. About 165 participants will receive either DT120 or a placebo for 12 weeks, followed by a 40-week period where everyone can take the drug. The main goal is to see if DT120 reduces depression symptoms better than placebo, measured by a standard rating scale.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Adams Clinical Boston

    RECRUITING

    Boston, Massachusetts, 02116, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Adams Clinical Harlem

    RECRUITING

    New York, New York, 10029, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Adams Clinical Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cedar Clinical Research

    RECRUITING

    Draper, Utah, 84020, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Atlanta

    RECRUITING

    Atlanta, Georgia, 30331, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Decatur

    RECRUITING

    Decatur, Georgia, 30030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • CenExel Savannah

    RECRUITING

    Savannah, Georgia, 31405, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Charter Research

    NOT_YET_RECRUITING

    Orlando, Florida, 32803, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Cleveland Clinic

    NOT_YET_RECRUITING

    Cleveland, Ohio, 44113, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Coastal Carolina Research

    RECRUITING

    North Charleston, South Carolina, 29405, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Inner Space Research

    RECRUITING

    Orem, Utah, 84058, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Lighthouse Psychiatry

    NOT_YET_RECRUITING

    Gilbert, Arizona, 85234, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Mountain View Clinical Research, Inc

    RECRUITING

    Denver, Colorado, 80209, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Preferred Research Partners, Inc.

    RECRUITING

    Little Rock, Arkansas, 72211, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Psychedelic Science Institute

    NOT_YET_RECRUITING

    Santa Monica, California, 90404, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UCSF Department of Neurology

    NOT_YET_RECRUITING

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Uptown Research Institute

    RECRUITING

    Chicago, Illinois, 60640, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Portland Healthcare System

    NOT_YET_RECRUITING

    Vancouver, Washington, 98661, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.