Could adding a migraine drug boost depression treatment?
NCT ID NCT06500624
First seen Oct 31, 2025 · Last updated May 09, 2026 · Updated 25 times
Summary
This study tested whether adding pizotifen (a migraine medication) to the standard antidepressant escitalopram works better than escitalopram alone for major depression. 88 newly diagnosed patients aged 14-70 took part. Researchers measured symptom changes using the PHQ-9 questionnaire. The goal was to see if the combination leads to greater improvement in depressive symptoms.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Riphah International University
Rawalpindi, Punjab Province, 00666, Pakistan
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