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Could a new set of dentures sharpen an aging mind?

NCT ID NCT06688669

Knowledge-focused Sponsor: Istanbul University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 27, 2026 · Last updated Aug 28, 2026 · Updated 1 time

Summary

This study looks at whether getting new removable dentures can affect cognitive skills and physical function in people over 60. Participants who need complete or partial dentures will take tests for memory, thinking, and mobility before getting their dentures, then again three weeks and three months later. The researchers will compare the test scores over time to see if denture use is linked to any changes. They will also measure how satisfied participants are with their new dentures.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Fabrication of complete or removable partial dentures
What this could lead to
If wearing new dentures improves cognitive and physical function in older adults, it could point to a simple, non-drug way to support healthy aging.
What could go wrong
This is an observational study with no control group, so any changes in test scores might be due to practice or other factors, not the dentures. Also, the follow-up is short, so long-term effects remain unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

71 people

The number who actually took part.

Started

Mar 2025

Finished

Sep 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients over the age of 60 who apply to Istanbul University Faculty of Dentistry to receive removable dentures.

Ages

60 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients over the age of 60 * No systemic condition that would prevent the fabrication of removable dentures * Need for new removable dentures for both jaws * Ability to read and understand the questions in the tests and surveys * No barriers to communication or self-expression * No significant physical disability affecting functionality * No history of cancer or surgical operation in the head and neck region * No conditions or medications that could limit test performance (e.g., Parkinson's disease) Exclusion Criteria: * Patients under the age of 60 * Patients who do not require new removable dentures * Patients whose missing teeth can be restored with fixed prosthetic restorations and who do not need removable dentures * Patients who are illiterate * Patients with systemic conditions that prevent the fabrication of removable dentures * Patients with conditions like Parkinson's disease that could restrict test performance or who use medications with side effects causing unwanted convulsions * Patients with significant balance issues, who frequently lose balance while walking * Geriatric patients with temporary or permanent memory loss * Patients with any history of cancer in the head and neck region * Patients with severe difficulty in communication and self-expression * Patients who are not willing to participate in the study

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Denture, complete Denture, partial, removable Edentulism

Contacts and locations

Locations

  • Istanbul University Faculty of Dentistry

    Istanbul, Vezneciler, Turkey (Türkiye)

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