Vacuum dressing may cut infection in dirty surgical wounds
NCT ID NCT04042259
First seen Jul 10, 2026 · Last updated Jul 10, 2026
Summary
This trial investigates whether using a negative pressure wound therapy device (a vacuum dressing) for delayed primary closure can reduce wound infections and other complications in patients with contaminated or dirty abdominal wounds. Participants are adults who have had an open abdomen after surgery and are at high risk for infection. The study compares outcomes to a historical group that did not receive the device.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Negative pressure wound therapy device (Abthera, VERAFLO, Prevena)
- What this could lead to
- If successful, this approach could lower infection rates and shorten healing time for patients with dirty abdominal wounds after surgery.
- What could go wrong
- This is a small, single-center study with no control group, and earlier research has shown mixed results. The therapy may not reduce complications and could increase costs.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Froedtert Hospital
Milwaukee, Wisconsin, 53226, United States