New Long-Acting drug for rare hormone tumors tested, but study stopped early

NCT ID NCT05364944

First seen Nov 17, 2025 · Last updated May 06, 2026 · Updated 27 times

Summary

This early-stage study tested a new formulation of octreotide (Debio 4126) that lasts 12 weeks, aiming to control hormone levels in people with acromegaly or certain neuroendocrine tumors. Only 19 participants were enrolled before the study was terminated. The goal was to measure how the drug behaves in the body and check its safety.

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Contacts and locations

Locations

  • AP-HM - Hôpital de la Conception, Service d'Endocrinologie et Centre de Référence des Maladies Rares de l'hypophyse

    Marseille, 13385, France

  • AP-HP Hopital Bicetre

    Le Kremlin-Bicêtre, 94270, France

  • CHU Angers

    Angers, 49933, France

  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano

    Milan, 20122, Italy

  • Hospital Universitario Virgen del Rocio

    Seville, 41013, Spain

  • Hospital de la Santa Creu i Sant Pau Barcelon

    Barcelona, 08041, Spain

  • Mazowiecki Szpital Brodnowski - Zespol Oddzialow Chorob Wewnetrznych, Endokrynologii i Diabetologii

    Warsaw, 03-242, Poland

  • Medicover Praxis fur Neuroendokrinologie

    Munich, 81667, Germany

  • Rabin Medical Center, Beilinson Hospital, Clalit Health Services by Rabin Medical Center, Beilinson Hospita

    Petah Tikva, 49100, Israel

  • Rigshospitalet, Endokrinologisk afdeling

    Copenhagen, 2200, Denmark

  • Royal Free London NHS Foundation Trust

    London, NW3 2QG, United Kingdom

  • Sheba Medical Center, Endocrine institute

    Ramat Gan, 5265601, Israel

  • University Hospital Coventry, WISDEM Centre, UHCW NHS Trust

    Coventry, CV2 2DX, United Kingdom

  • Uniwersyteckie Centrum Kliniczne im. Prof. K. Gibinskiego Slaskiego Uniwersytetu Medycznego w Katowicach

    Katowice, 40-514, Poland

Conditions

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