Could some AML patients ditch chemo pills after a year?

NCT ID NCT06557421

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether people with acute myeloid leukemia (AML) who have responded well to a year of treatment with venetoclax and azacitidine can safely stop taking these drugs. Researchers will monitor 50 patients closely for signs of relapse and compare them to a similar group that continued treatment. The goal is to see if stopping therapy can maintain remission while reducing medication side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

venetoclax and azacitidine

What this could lead to

If successful, this could show that some AML patients can safely stop these drugs after a year of treatment, reducing side effects and medication burden.

What could go wrong

This is a small, early-phase study with only 50 participants. Stopping treatment may lead to relapse, and results may not apply to all AML patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut Paoli-Calmettes

    RECRUITING

    Marseille, 13273, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact