Antibiotic reduction strategy found safe for severe sepsis

NCT ID NCT01626612

First seen May 12, 2026 · Last updated Jun 12, 2026 · Updated 10 times

Summary

This study looked at whether doctors can safely reduce or narrow the antibiotics given to patients with severe sepsis once the exact germ causing the infection is identified. The goal was to see if this approach, called de-escalation, is as good as continuing the original broad antibiotics. The trial involved 120 adults in intensive care units and measured how long they stayed in the ICU, death rates, and the rise of drug-resistant germs.

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Contacts and locations

Locations

  • Assistance Publique Hopitaux de Marseille

    Marseille, 13354, France

Conditions

Explore the condition pages connected to this study.