New hope for rare kidney disease: drug trial targets severe cases
NCT ID NCT04580420
First seen Jan 03, 2026 · Last updated May 16, 2026 · Updated 20 times
Summary
This study tests an experimental drug called DCR-PHXC in people with primary hyperoxaluria type 1 (PH1) who have severe kidney damage, whether or not they are on dialysis. The goal is to see if the drug can safely lower oxalate levels in the blood, which may help control the disease. About 28 participants, including children and adults, will take part. Because lifelong treatment is likely needed, this is not a cure but aims to manage the condition.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Clinical Trial Site
ACTIVE_NOT_RECRUITINGSan Francisco, California, 94143, United States
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Clinical Trial Site
ACTIVE_NOT_RECRUITINGBoston, Massachusetts, 02115, United States
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Clinical Trial Site
RECRUITINGRochester, Minnesota, 55905, United States
Contact
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Clinical Trial Site
ACTIVE_NOT_RECRUITINGNew York, New York, 10016, United States
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Clinical Trial Site
WITHDRAWNBron, 69677, France
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Clinical Trial Site
WITHDRAWNParis, 75019, France
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Clinical Trial Site
RECRUITINGBonn, 53127, Germany
Contact
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Clinical Trial Site
WITHDRAWNHeidelberg, 69120, Germany
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Clinical Trial Site
WITHDRAWNRoma, 00165, Italy
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Clinical Trial Site
RECRUITINGBeirut, 00001, Lebanon
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Clinical Trial Site
WITHDRAWNCasablanca, 2025, Morocco
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Clinical Trial Site
WITHDRAWNOradea, 410469, Romania
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Clinical Trial Site
WITHDRAWNOradea, 410562, Romania
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Clinical Trial Site
RECRUITINGBarcelona, 08035, Spain
Contact
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Clinical Trial Site
WITHDRAWNSanta Cruz de Tenerife, 38320, Spain
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Clinical Trial Site
RECRUITINGDubai, +971, United Arab Emirates
Contact
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Clinical Trial Site
WITHDRAWNLondon, NWG 2Q3, United Kingdom
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Clinical Trial Site
RECRUITINGLondon, WC1N3JH, United Kingdom
Contact
Conditions
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