Breast cancer study tests avoiding surgery with hormone pills
NCT ID NCT06075953
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 24 times
Summary
This study tests whether active monitoring with hormone therapy can safely manage ductal carcinoma in situ (DCIS), a very early form of breast cancer, instead of immediate surgery. About 400 women with hormone-sensitive DCIS will receive either standard or experimental hormone therapy and have MRI scans at 3 and 6 months. If the scans show low risk, they may continue monitoring; if not, they proceed to surgery.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Locations
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Atrium Health Wake Forest Baptist Comprehensive Cancer Center
RECRUITINGWinston-Salem, North Carolina, 27157, United States
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Berkeley Outpatient Center
RECRUITINGBerkeley, California, 94158, United States
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Bryn Mawr Hospital
ACTIVE_NOT_RECRUITINGBryn Mawr, Pennsylvania, 19010, United States
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City of Hope
RECRUITINGSouth Pasadena, California, 91030, United States
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City of Hope - Lennar Foundation Cancer Center
RECRUITINGIrvine, California, 92618, United States
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City of Hope -Duarte Cancer Center
RECRUITINGDuarte, California, 91010, United States
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Duke Cancer Institute
RECRUITINGDurham, North Carolina, 27710, United States
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Englewood Hospital and Medical Center
RECRUITINGEnglewood, New Jersey, 07631, United States
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Health Partners - Frauenshuh Cancer Center
RECRUITINGSaint Louis Park, Minnesota, 55426, United States
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Health Partners - Regions Hospital
RECRUITINGSaint Paul, Minnesota, 55101, United States
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Hennepin Healthcare -Minneapolis
RECRUITINGMinneapolis, Minnesota, 55404, United States
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Huntsman Cancer Institute
RECRUITINGSalt Lake City, Utah, 84112, United States
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Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 10029, United States
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John Muir Health
RECRUITINGWalnut Creek, California, 94598, United States
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Lankenau Medical Center
ACTIVE_NOT_RECRUITINGWynnewood, Pennsylvania, 19096, United States
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Maple Grove Cancer Center
RECRUITINGMaple Grove, Minnesota, 55369, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Mount Sinai Chelsea
RECRUITINGNew York, New York, 10011, United States
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Mount Sinai Union Square
RECRUITINGNew York, New York, 10003, United States
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Mount Sinai West
RECRUITINGNew York, New York, 10019, United States
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Paoli Hospital
ACTIVE_NOT_RECRUITINGPaoli, Pennsylvania, 19301, United States
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UCLA
RECRUITINGLos Angeles, California, 90095, United States
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UCSF
RECRUITINGSan Francisco, California, 94158, United States
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University of Chicago Medical Center
RECRUITINGChicago, Illinois, 60637, United States
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55455, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
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Winship Cancer Institute, Emory University
RECRUITINGAtlanta, Georgia, 30322, United States
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Contact Email: •••••@•••••
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Conditions
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