Can a better MRI scan help shrink pancreatic tumors for surgery?

NCT ID NCT06173310

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a special MRI technique called DCE-MRI can guide chemotherapy for people with borderline resectable pancreatic cancer. The goal is to see if this imaging method can better track tumor blood flow and help doctors decide if the treatment is working, so they can switch therapies if needed. About 50 adults with newly diagnosed, untreated pancreatic cancer will participate. The study focuses on improving imaging accuracy, not on directly treating the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DCE-MRI imaging with a portable perfusion phantom (P4 device)

What this could lead to

If successful, this imaging method could help doctors choose the most effective chemotherapy for each patient, potentially making more pancreatic tumors removable by surgery.

What could go wrong

This is a small, early-stage study focused on imaging accuracy, not treatment outcomes. The approach may not improve survival or surgical success rates.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Indiana University Medical Center

    RECRUITING

    Indianapolis, Indiana, 46202, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••