Brain zaps for depression: new hope or hype?

NCT ID NCT03653858

First seen Apr 30, 2026 · Last updated Jun 13, 2026 · Updated 9 times

Summary

This study tested a treatment called deep brain stimulation (DBS) for people with severe depression that hasn't gotten better with standard treatments. 46 adults received either active brain stimulation or a sham (fake) procedure to see if it could reduce their depression symptoms. The goal was to find a new option for those who have run out of effective treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University Hospital Freiburg

    Freiburg im Breisgau, Baden-Wurttemberg, 79106, Germany

  • Université Grenoble Alpes

    Grenoble, 38043, France

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.