New hope for ALS: experimental drug aims to slow muscle decline

NCT ID NCT05407324

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an experimental drug, dazucorilant, in 279 adults with ALS (Lou Gehrig's disease). The goal is to see if the drug can slow the loss of muscle function and improve quality of life over 24 weeks. Participants will receive either the drug or a placebo, and researchers will monitor safety and changes in daily abilities.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

amyotrophic lateral sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • 062

    RECRUITING

    Phoenix, Arizona, 85013, United States

  • 108

    ACTIVE_NOT_RECRUITING

    Leuven, 3000, Belgium

  • 115

    ACTIVE_NOT_RECRUITING

    Barcelona, 08035, Spain

  • 194

    ACTIVE_NOT_RECRUITING

    Valencia, 46026, Spain

  • 253

    ACTIVE_NOT_RECRUITING

    Dublin, D09 YD60, Ireland

  • 254

    ACTIVE_NOT_RECRUITING

    Warsaw, 01-684, Poland

  • 255

    ACTIVE_NOT_RECRUITING

    Berlin, 13353, Germany

  • 256

    ACTIVE_NOT_RECRUITING

    Tours, 37000, France

  • 257

    ACTIVE_NOT_RECRUITING

    Limoges, 87042, France

  • 258

    ACTIVE_NOT_RECRUITING

    Lille, 59037, France

  • 259

    ACTIVE_NOT_RECRUITING

    Nice, 06001, France

  • 260

    ACTIVE_NOT_RECRUITING

    Hanover, 30625, Germany

  • 261

    ACTIVE_NOT_RECRUITING

    Marseille, 13385, France

  • 262

    ACTIVE_NOT_RECRUITING

    Paris, 75651, France

  • 263

    ACTIVE_NOT_RECRUITING

    Stoke-on-Trent, ST4 6QG, United Kingdom

  • 264

    RECRUITING

    Utrecht, 3584 CW, Netherlands

  • 265

    ACTIVE_NOT_RECRUITING

    Jena, 7747, Germany

  • 267

    ACTIVE_NOT_RECRUITING

    Rostock, 18147, Germany

  • 268

    ACTIVE_NOT_RECRUITING

    Dresden, 1307, Germany

  • 269

    ACTIVE_NOT_RECRUITING

    Ulm, 89081, Germany

  • 270

    RECRUITING

    Bonn, 53127, Germany

  • 273

    ACTIVE_NOT_RECRUITING

    Montreal, Quebec, H3A2B4, Canada

  • 274

    ACTIVE_NOT_RECRUITING

    Warsaw, 02-473, Poland

  • 278

    RECRUITING

    San Francisco, California, 94109, United States

  • 282

    ACTIVE_NOT_RECRUITING

    Málaga, 29010, Spain

  • 283

    ACTIVE_NOT_RECRUITING

    Bydgoszcz, 85-163, Poland

  • 287

    RECRUITING

    Neptune City, New Jersey, 07753, United States

  • 302

    ACTIVE_NOT_RECRUITING

    Barcelona, 08003, Spain

  • 303

    ACTIVE_NOT_RECRUITING

    Madrid, 28046, Spain

  • 353

    RECRUITING

    New York, New York, 10032, United States

  • 385

    ACTIVE_NOT_RECRUITING

    Krakow, 30721, Poland

  • 386

    ACTIVE_NOT_RECRUITING

    München, 81675, Germany

  • 422

    ACTIVE_NOT_RECRUITING

    Bron, 69500, France

  • 423

    ACTIVE_NOT_RECRUITING

    Montpellier, 42395, France

  • 425

    ACTIVE_NOT_RECRUITING

    Hamilton, Ontario, L8N 3Z5, Canada