New smart drug DAY301 takes aim at Hard-to-Treat cancers

NCT ID NCT06752681

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 19 times

Summary

This early-phase study tests a new drug called DAY301 in people with advanced solid tumors (like ovarian, lung, or breast cancer) that have not responded to standard treatments. DAY301 is designed to deliver a powerful chemotherapy directly to cancer cells that carry a specific marker (PTK7). The main goals are to check safety, find the best dose, and see if the drug can shrink tumors. About 254 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Site: 001-039

    RECRUITING

    New York, New York, 10021, United States

  • Site: 001-057

    RECRUITING

    San Antonio, Texas, 78229, United States

  • Site: 001-058

    RECRUITING

    New Haven, Connecticut, 06510, United States

  • Site: 001-059

    RECRUITING

    Grand Rapids, Michigan, 49546, United States

  • Site: 001-060

    RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Site: 001-063

    RECRUITING

    Lake Mary, Florida, 32746, United States

  • Site: 001-064

    RECRUITING

    Sarasota, Florida, 34232, United States

  • Site: 001-065

    RECRUITING

    Nashville, Tennessee, 37203, United States

  • Site: 001-069

    RECRUITING

    Houston, Texas, 77030, United States

  • Site: 001-073

    RECRUITING

    Oklahoma City, Oklahoma, 73104, United States

  • Site: 011-005

    RECRUITING

    Toronto, Ontario, M5G 2M9, Canada

  • Site: 011-013

    RECRUITING

    Vancouver, British Columbia, V5Z 4E6, Canada

Conditions

Explore the condition pages connected to this study.