New drug cocktail targets tough cancers in kids

NCT ID NCT02389309

First seen Oct 31, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This early-phase trial tests the safety and best dose of a three-drug combination (dasatinib, temsirolimus, and cyclophosphamide) in children and young adults (ages 1 to 21) with advanced solid tumors that have come back or not responded to standard treatments. The goal is to find the highest safe dose and see how well the drugs work together to stop tumor growth. The study is not yet recruiting and involves 14 participants at MD Anderson Cancer Center.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

Explore the condition pages connected to this study.