New hope for tough leukemia: dasatinib tested after standard therapy fails

NCT ID NCT06055621

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial is testing the drug dasatinib alone in adults with acute myeloid leukemia (AML) whose cancer did not respond to the usual combination of venetoclax and azacitidine. The main goal is to see if dasatinib can shrink the leukemia after two months of treatment. About 35 people will take dasatinib daily for up to 3 months, and doctors will check their blood and bone marrow for signs of remission.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Dasatinib (a targeted cancer drug taken daily by mouth)

What this could lead to

If it works, this could offer a new treatment option for AML patients who have not responded to standard therapy.

What could go wrong

This is a small, early-phase trial with only 35 participants. It may not work for everyone, and dasatinib can cause side effects like fluid retention or heart issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact