Early trial tests cancer drug for dangerous blood clot disorder
NCT ID NCT05671757
Summary
This early-stage study is testing whether a medication called daratumumab, already used for some cancers, is safe for people with antiphospholipid syndrome (APS), a disorder that causes dangerous blood clots. Up to 22 adults with APS will receive the drug through an IV to see what dose is safest and if it can lower the harmful antibodies that cause clotting. The main goal is to check for serious side effects, while also seeing if the treatment reduces the antibodies linked to the disease.
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Contacts and locations
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Locations
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Duke University
RECRUITINGDurham, North Carolina, 27710, United States
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Hospital for Special Surgery
RECRUITINGNew York, New York, 10021, United States
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Johns Hopkins University
RECRUITINGBaltimore, Maryland, 21205, United States
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Mayo Clinic Rochester
COMPLETEDRochester, Minnesota, 55905, United States
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NYU Langone
RECRUITINGNew York, New York, 10016, United States
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Northwell Health
RECRUITINGGreat Neck, New York, 11021, United States
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University of Michigan
RECRUITINGAnn Arbor, Michigan, 48109, United States
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Weill Cornell
RECRUITINGNew York, New York, 10021, United States
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Conditions
Explore the condition pages connected to this study.