New hope for smoldering myeloma: daratumumab doses tested

NCT ID NCT02316106

First seen Apr 26, 2026 · Last updated May 06, 2026 · Updated 4 times

Summary

This study tested three different schedules of the drug daratumumab in 123 people with smoldering multiple myeloma, a condition that can turn into active cancer. The goal was to see which dose schedule works best to control the disease and prevent it from progressing. Participants received daratumumab infusions on different timings, and researchers measured how many achieved a complete response or had their disease get worse.

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Contacts and locations

Locations

  • Study site

    Little Rock, Arkansas, United States

  • Study site

    Jacksonville, Florida, United States

  • Study site

    West Palm Beach, Florida, United States

  • Study site

    Atlanta, Georgia, United States

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    Boston, Massachusetts, United States

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    Ann Arbor, Michigan, United States

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    St Louis, Missouri, United States

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    Hackensack, New Jersey, United States

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    New York, New York, United States

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    Chapel Hill, North Carolina, United States

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    Cincinnati, Ohio, United States

  • Study site

    Columbus, Ohio, United States

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    Philadelphia, Pennsylvania, United States

  • Study site

    Nashville, Tennessee, United States

  • Study site

    Seattle, Washington, United States

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    Box Hill, Australia

  • Study site

    Concord, Australia

  • Study site

    Melbourne, Australia

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    Woodville South, Australia

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    Calgary, Alberta, Canada

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    Edmonton, Alberta, Canada

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    Toronto, Ontario, Canada

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    Brno, Czechia

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    Hradec Králové, Czechia

  • Study site

    Prague, Czechia

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    Lille, France

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    Nantes, France

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    Paris, France

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    Pierre-Bénite, France

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    Rennes, France

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    Berlin, Germany

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    Chemnitz, Germany

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    Essen, Germany

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    Heidelberg, Germany

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    Mainz, Germany

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    München, Germany

  • Study site

    Tübingen, Germany

  • Study site

    Würzburg, Germany

  • Study site

    Haifa, Israel

  • Study site

    Jerusalem, Israel

  • Study site

    Petah Tikva, Israel

  • Study site

    Tel Aviv, Israel

  • Study site

    Amsterdam, Netherlands

  • Study site

    Rotterdam, Netherlands

  • Study site

    Utrecht, Netherlands

  • Study site

    Nizhny Novgorod, Russia

  • Study site

    Petrozavodsk, Russia

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    Ryazan, Russia

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    Saint Petersburg, Russia

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    Ankara, Turkey (Türkiye)

  • Study site

    Antalya, Turkey (Türkiye)

  • Study site

    Izmir, Turkey (Türkiye)

  • Study site

    Samsun, Turkey (Türkiye)

  • Study site

    Cardiff, United Kingdom

  • Study site

    Nottingham, United Kingdom

  • Study site

    Southampton, United Kingdom

  • Study site

    Surrey, United Kingdom

Conditions

Explore the condition pages connected to this study.