New drug combo shows promise for untreated CLL patients

NCT ID NCT03447808

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 22 times

Summary

This early-phase study tested a combination of two drugs, daratumumab and ibrutinib, in 15 people with untreated chronic lymphocytic leukemia (CLL) who needed treatment. The goal was to see how safe the combination is and how well it works at controlling the disease. Participants received both drugs, and researchers tracked side effects and cancer response. While the treatment aims to control CLL, it is not a cure, and ongoing management may still be needed.

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Contacts and locations

Locations

  • Ohio State University Comprehensive Cancer Center

    Columbus, Ohio, 43210, United States

Conditions

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