Could a Two-Drug combo ease heart failure and lung pressure?
NCT ID NCT06778330
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study tested whether adding sildenafil to dapagliflozin helps heart failure patients who also have high blood pressure in their lungs. 100 participants received either dapagliflozin alone or both drugs. Researchers measured changes in heart pumping strength and lung artery pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dapagliflozin and sildenafil
- What this could lead to
- If it works, this could point toward a better combination treatment for heart failure patients who also have high blood pressure in their lungs.
- What could go wrong
- This is a small, completed trial with only 100 participants, so results may not apply to everyone. The combination may not improve heart function more than dapagliflozin alone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Fayoum University
Al Fayyum, Egypt
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Other studies related to the condition(s) this trial covers.
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