Could a Two-Drug combo ease heart failure and lung pressure?
NCT ID NCT06778330
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This completed study tested whether adding sildenafil to dapagliflozin helps heart failure patients who also have high blood pressure in their lungs. 100 participants received either dapagliflozin alone or both drugs. Researchers measured changes in heart pumping strength and lung artery pressure.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
dapagliflozin and sildenafil
What this could lead to
If it works, this could point toward a better combination treatment for heart failure patients who also have high blood pressure in their lungs.
What could go wrong
This is a small, completed trial with only 100 participants, so results may not apply to everyone. The combination may not improve heart function more than dapagliflozin alone.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Fayoum University
Al Fayyum, Egypt