Could a muscle relaxant make back surgery recovery less painful?
NCT ID NCT03762109
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether dantrolene, a non-sedating muscle relaxant, can improve pain control and reduce agitation in adults undergoing lumbar fusion surgery. Participants receive either dantrolene or a placebo pill before and after surgery. The goal is to see if dantrolene improves overall pain relief and sedation levels compared to standard care alone.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dantrolene (a muscle relaxant)
- What this could lead to
- If it works, this could offer a better way to manage pain after back surgery without relying solely on opioids.
- What could go wrong
- This is a small, early-phase study, so results may not apply to everyone. Dantrolene can cause muscle weakness or liver issues in rare cases.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.