New combo therapy aims to keep stage III melanoma away after surgery

NCT ID NCT04666272

First seen Feb 21, 2026 · Last updated May 16, 2026 · Updated 13 times

Summary

This study looks at how well and how safely two drugs, dabrafenib and trametinib, work together after surgery to stop stage III melanoma from returning in Chinese patients with a specific gene change (BRAF V600). About 78 adults who have had their melanoma completely removed will take these drugs as directed by their doctor. The main goal is to see how long they stay cancer-free.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Fuzhou, Fujian, 350014, China

  • Novartis Investigative Site

    Zhengzhou, Henan, 410100, China

  • Novartis Investigative Site

    Wuhan, Hubei, 430022, China

  • Novartis Investigative Site

    Changsha, Hunan, 410013, China

  • Novartis Investigative Site

    Nanjing, Jiangsu, 210008, China

  • Novartis Investigative Site

    Kunming, Yunnan, 650106, China

  • Novartis Investigative Site

    Hangzhou, Zhejiang, 310022, China

  • Novartis Investigative Site

    Beijing, 100036, China

Conditions

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