New pill could clear psoriasis skin in 12 weeks
NCT ID NCT07489885
First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 3 times
Summary
This Phase 2 trial tests an experimental oral drug called D-2570 in 75 adults with moderate to severe plaque psoriasis. Participants are randomly assigned to receive either D-2570 or a placebo tablet for 12 weeks. The main goal is to see if the drug can achieve at least a 90% improvement in psoriasis severity (PASI-90). The study is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- D-2570 tablet
- What this could lead to
- If successful, this could point toward a new oral treatment option for moderate to severe plaque psoriasis, potentially offering better skin clearance.
- What could go wrong
- This is an early Phase 2 trial with only 75 participants, so results may not apply to everyone. The drug may not work better than placebo or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Study Center
RECRUITINGBirmingham, Alabama, 35244, United States
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Study Center
NOT_YET_RECRUITINGPhoenix, Arizona, 85008, United States
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Study Center
RECRUITINGChula Vista, California, 91910, United States
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Study Center
NOT_YET_RECRUITINGFountain Valley, California, 92708, United States
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Study Center
NOT_YET_RECRUITINGFremont, California, 94538, United States
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Study Center
NOT_YET_RECRUITINGLos Angeles, California, 90017, United States
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Study Center
NOT_YET_RECRUITINGLos Angeles, California, 90024, United States
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Study Center
NOT_YET_RECRUITINGSan Diego, California, 92123, United States
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Study Center
NOT_YET_RECRUITINGFort Lauderdale, Florida, 33308, United States
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Study Center
NOT_YET_RECRUITINGMiramar, Florida, 33027, United States
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Study Center
NOT_YET_RECRUITINGOcala, Florida, 34470, United States
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Study Center
NOT_YET_RECRUITINGTampa, Florida, 33607, United States
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Study Center
NOT_YET_RECRUITINGSandy Springs, Georgia, 30328, United States
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Study Center
NOT_YET_RECRUITINGSavannah, Georgia, 31419, United States
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Study Center
NOT_YET_RECRUITINGIdaho Falls, Idaho, 83404, United States
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Study Center
NOT_YET_RECRUITINGClarksville, Indiana, 40241, United States
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Study Center
NOT_YET_RECRUITINGLouisville, Kentucky, 40241, United States
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Study Center
NOT_YET_RECRUITINGMayfield Heights, Ohio, 44124, United States
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Study Center
NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19103, United States
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Study Center
RECRUITINGSan Antonio, Texas, 78218, United States
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