New pill could clear psoriasis skin in 12 weeks

NCT ID NCT07489885

First seen Jun 25, 2026 · Last updated Jul 10, 2026 · Updated 3 times

Summary

This Phase 2 trial tests an experimental oral drug called D-2570 in 75 adults with moderate to severe plaque psoriasis. Participants are randomly assigned to receive either D-2570 or a placebo tablet for 12 weeks. The main goal is to see if the drug can achieve at least a 90% improvement in psoriasis severity (PASI-90). The study is currently recruiting.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
D-2570 tablet
What this could lead to
If successful, this could point toward a new oral treatment option for moderate to severe plaque psoriasis, potentially offering better skin clearance.
What could go wrong
This is an early Phase 2 trial with only 75 participants, so results may not apply to everyone. The drug may not work better than placebo or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Study Center

    RECRUITING

    Birmingham, Alabama, 35244, United States

  • Study Center

    NOT_YET_RECRUITING

    Phoenix, Arizona, 85008, United States

  • Study Center

    RECRUITING

    Chula Vista, California, 91910, United States

  • Study Center

    NOT_YET_RECRUITING

    Fountain Valley, California, 92708, United States

  • Study Center

    NOT_YET_RECRUITING

    Fremont, California, 94538, United States

  • Study Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90017, United States

  • Study Center

    NOT_YET_RECRUITING

    Los Angeles, California, 90024, United States

  • Study Center

    NOT_YET_RECRUITING

    San Diego, California, 92123, United States

  • Study Center

    NOT_YET_RECRUITING

    Fort Lauderdale, Florida, 33308, United States

  • Study Center

    NOT_YET_RECRUITING

    Miramar, Florida, 33027, United States

  • Study Center

    NOT_YET_RECRUITING

    Ocala, Florida, 34470, United States

  • Study Center

    NOT_YET_RECRUITING

    Tampa, Florida, 33607, United States

  • Study Center

    NOT_YET_RECRUITING

    Sandy Springs, Georgia, 30328, United States

  • Study Center

    NOT_YET_RECRUITING

    Savannah, Georgia, 31419, United States

  • Study Center

    NOT_YET_RECRUITING

    Idaho Falls, Idaho, 83404, United States

  • Study Center

    NOT_YET_RECRUITING

    Clarksville, Indiana, 40241, United States

  • Study Center

    NOT_YET_RECRUITING

    Louisville, Kentucky, 40241, United States

  • Study Center

    NOT_YET_RECRUITING

    Mayfield Heights, Ohio, 44124, United States

  • Study Center

    NOT_YET_RECRUITING

    Philadelphia, Pennsylvania, 19103, United States

  • Study Center

    RECRUITING

    San Antonio, Texas, 78218, United States

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